What is the correct dose for OTFC?

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The correct dose for OTFC, which stands for Oral Transmucosal Fentanyl Citrate, is 800 mcg delivered transmuccosally. This formulation is specifically designed for the management of breakthrough pain, particularly in patients who are already on a stable dose of opioid therapy for chronic pain and requires a quick-acting system for the relief of sudden pain episodes.

Transmucosal delivery is ideal for fentanyl as it allows for rapid absorption across the mucous membranes, providing effective analgesia in a short amount of time. The 800 mcg dosage is intended to deliver a potent effect while minimizing the risk of overdose when used appropriately in the intended patient population.

Different routes of administration and dosages, such as those given intravenously or intramuscularly, are intended for various contexts of pain management but do not apply to OTFC. The emphasis on the transmucosal route is crucial to its proper use in clinical practice.

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